<meta name="GENERATOR" content="OpenOffice 4.1.6 (Unix)"/> <meta name="AUTHOR" content="Chaojun Li"/> <meta name="CREATED" content="20140911;2440000"/> <meta name="CHANGEDBY" content="Administrator"/> <meta name="CHANGED" content="20220812;7540000"/> <meta name="AppVersion" content="12.0000"/> <meta name="Company" content="MMCB"/> <meta name="DocSecurity" content="0"/> <meta name="HyperlinksChanged" content="false"/> <meta name="LinksUpToDate" content="false"/> <meta name="ScaleCrop" content="false"/> <meta name="ShareDoc" content="false"/> <style type="text/css"> <!-- @page { size: 8.27in 11.69in; margin-left: 1.25in; margin-right: 1.18in; margin-top: 1in; margin-bottom: 1in } P { margin-bottom: 0.08in; direction: ltr; color: #000000; text-align: justify; widows: 0; orphans: 0 } A:link { color: #0000ff; so-language: zxx } --> </style><p align="CENTER" style="margin-bottom: 0in"><font face="文泉驛正黑"><span lang="zh-CN"><font size="4"><b>博士研究生导师简介</b></font></span></font></p><table width="591" border="1" bordercolor="#00000a" cellpadding="7" cellspacing="0"> <col width="41"/> <col width="12"/> <col width="22"/> <col width="74"/> <col width="174"/> <col width="182"/> <tr> <td width="41" height="84"> <p align="CENTER"><font face="文泉驛正黑"><span lang="zh-CN">姓名</span></font></p> </td> <td colspan="2" width="47"> <p align="CENTER"><font face="文泉驛正黑"><span lang="zh-CN">张青</span></font></p> </td> <td width="74"> <p align="CENTER"><font face="文泉驛正黑"><span lang="zh-CN">研究方向：</span></font></p> </td> <td width="174"> <p align="LEFT" style="margin-bottom: 0in">1.Hedgehog<font face="文泉驛正黑"><span lang="zh-CN">信号转导调节研究</span></font></p> <p align="LEFT" style="margin-bottom: 0in">2.<font face="文泉驛正黑"><span lang="zh-CN">线粒体疾病机制研究</span></font></p> <p align="LEFT">3.<font face="文泉驛正黑"><span lang="zh-CN">溶酶体疾病机制研究</span></font></p> </td> <td rowspan="2" width="182"> <p align="CENTER"><img src="/_upload/article/images/c2/0f/fb5b0a284ccaab8375a2bb6ecd16/57139949-9ebb-4e78-9343-f75ef66f794a.jpg" align="BOTTOM" width="180" height="200" border="0"/></p> </td> </tr> <tr> <td colspan="2" width="67" height="33"> <p align="CENTER"><font face="文泉驛正黑"><span lang="zh-CN">联系方式</span></font></p> </td> <td colspan="3" width="298"> <p align="LEFT"><a href="mailto:zhangqing@nicemice.cn">zhangqing@nicemice.cn</a><font face="文泉驛正黑"><span lang="zh-CN">；</span></font><font face="Times New Roman, serif">zhangqing@nju.edu.cn</font></p> </td> </tr> <tr valign="TOP"> <td colspan="5" width="379" height="70"> <p align="LEFT" style="margin-bottom: 0in"><font face="文泉驛正黑"><span lang="zh-CN">学术兼职：</span></font></p> <p align="LEFT" style="margin-left: 0.17in; margin-bottom: 0in"><font face="文泉驛正黑"><span lang="zh-CN">美国遗传学会会员</span></font></p> <p align="LEFT" style="margin-left: 0.17in"><font face="文泉驛正黑"><span lang="zh-CN">中国细胞生物学学会会员</span></font></p> </td> <td width="182"> <p align="CENTER"><br/> </p> </td> </tr> <tr> <td colspan="6" width="575" height="24"> <p align="CENTER"><font face="文泉驛正黑"><span lang="zh-CN"><b>个人</b><b>简介</b></span></font></p> </td> </tr> <tr> <td colspan="6" width="575" height="193"> <p style="margin-left: 0.02in; margin-bottom: 0in"><font face="文泉驛正黑"><span lang="zh-CN">张青，</span></font><font face="Damascus, serif">2002</font><font face="文泉驛正黑"><span lang="zh-CN">年获复旦大学理学博士学位，</span></font><font face="Damascus, serif">2003</font><font face="文泉驛正黑"><span lang="zh-CN">至</span></font><font face="Damascus, serif">2009</font><font face="文泉驛正黑"><span lang="zh-CN">年在美国德克萨斯大学西南医学中心</span></font><font face="Damascus, serif">(UT Southwestern Medical Center at Dallas)</font><font face="文泉驛正黑"><span lang="zh-CN">从事发育生物学领域的博士后研究工作，</span></font><font face="Damascus, serif">2009</font><font face="文泉驛正黑"><span lang="zh-CN">年</span></font><font face="Damascus, serif">7</font><font face="文泉驛正黑"><span lang="zh-CN">月起任南京大学模式动物研究所教授、博导。主要研究方向为以果蝇为模式动物， 运用遗传学</span></font><font face="Damascus, serif">, </font><font face="文泉驛正黑"><span lang="zh-CN">生物化学及分子生物学手段研究</span></font><font face="Damascus, serif">Hedgehog</font><font face="文泉驛正黑"><span lang="zh-CN">（</span></font><font face="Damascus, serif">Hh</font><font face="文泉驛正黑"><span lang="zh-CN">）</span></font><font face="Damascus, serif">/Hippo</font><font face="文泉驛正黑"><span lang="zh-CN">信号通路调节及线粒体功能稳态等分子机制。主持承担国家</span></font><font face="Damascus, serif">973</font><font face="文泉驛正黑"><span lang="zh-CN">计划、自然基金等项目和课题， 在</span></font><font face="Damascus, serif">Developmental Cell</font><font face="文泉驛正黑"><span lang="zh-CN">，</span></font><font face="Damascus, serif">PNAS</font><font face="文泉驛正黑"><span lang="zh-CN">，</span></font><font face="Damascus, serif">Cell Research</font><font face="文泉驛正黑"><span lang="zh-CN">，</span></font><font face="Damascus, serif">Molecular Cell</font><font face="文泉驛正黑"><span lang="zh-CN">等期刊发表重要论文多篇。</span></font></p> <p style="margin-left: 0.02in; margin-bottom: 0in"><br/> </p> <p style="margin-left: 0.02in"><br/> </p> </td> </tr> <tr> <td colspan="6" width="575" height="23"> <p align="CENTER"><font face="文泉驛正黑"><span lang="zh-CN"><b>代表性</b><b>论文</b></span></font><font face="Damascus, serif"><font size="1" style="font-size: 7pt"><b>[</b></font></font><font face="文泉驛正黑"><span lang="zh-CN"><font size="1" style="font-size: 7pt"><b>近</b></font></span></font><font face="Damascus, serif"><font size="1" style="font-size: 7pt"><b>5</b></font></font><font face="文泉驛正黑"><span lang="zh-CN"><font size="1" style="font-size: 7pt"><b>年通讯作者和第一作者</b></font></span></font><font face="Damascus, serif"><font size="1" style="font-size: 7pt"><b>]</b></font></font></p> </td> </tr> <tr> <td colspan="6" width="575" height="184"> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font face="Times New Roman, serif">1. </font><font face="Times New Roman, serif"><b>Zhang Q</b></font><font face="文泉驛正黑"><span lang="zh-CN"><font color="#333333">，</font></span></font><font face="Times New Roman, serif">Jiang J. (2021)</font><font color="#0f5ba0"><font face="Times New Roman, serif"> </font></font><font face="Times New Roman, serif"><a href="https://isisn.nsfc.gov.cn/egrantweb/project/rptcompletion/enter">Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination</a>.</font><font color="#999999"><font face="Times New Roman, serif"><i><b> </b></i></font></font><font face="Times New Roman, serif"><i><b>Int J Mol Sci</b></i></font><font face="Times New Roman, serif">. 22(24):13338.</font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in; background: #ffffff; widows: 2; orphans: 2"> <font color="#000000"><font face="Times New Roman, serif">2. Jiang W, Yao X, Shan Z, Li W, Gao Y, </font></font><font color="#000000"><font face="Times New Roman, serif"><b>Zhang Q</b></font></font><font color="#000000"><font face="Times New Roman, serif">. (2019) <a href="https://www.ncbi.nlm.nih.gov/pubmed/30925584">E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation.</a></font></font><font color="#000000"><font face="Times New Roman, serif"><i><b> J Mol Cell Biol.</b></i></font></font><font color="#000000"><font face="Times New Roman, serif"> 11(9):791-803.</font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font color="#000000"><font face="Times New Roman, serif">3. Zhou Z, Yao X, Pang S, Chen P, Jiang W, Shan Z, </font></font><font color="#000000"><font face="Times New Roman, serif"><b>Zhang Q</b></font></font><font color="#000000"><font face="Times New Roman, serif">. (2018) The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>J Mol Cell Biol</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 10(3):243-257.</font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font color="#000000"><font face="Times New Roman, serif">4. Chen P, Zhou Z, Yao X, Pang S, Liu M, Jiang W, Jiang J, </font></font><font color="#000000"><font face="Times New Roman, serif"><b>Zhang Q</b></font></font><font color="#000000"><font face="Times New Roman, serif">. (2017) Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A.</font></font><font color="#000000"><font face="Times New Roman, serif"><i><b> Sci Rep</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 7(1): 2891.</font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font color="#000000"><font face="Times New Roman, serif">5. Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, </font></font><font color="#000000"><font face="Times New Roman, serif"><b>Zhang Q</b></font></font><font color="#000000"><font face="Times New Roman, serif">. (2015) Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>Dev Cell</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 34(1):58-72. </font></font> </p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font color="#000000"><font face="Times New Roman, serif">6. An J, Ren S, Murphy S, Dalangood S, Chang C, Pang X, Cui Y, Wang L, Pan Y, Zhang X, Zhu Y, Wang C, Halling G, Cheng L, Sukov W, Karnes R, Vasmatzis G, </font></font><font color="#000000"><font face="Times New Roman, serif"><b>Zhang Q</b></font></font><font color="#000000"><font face="Times New Roman, serif">, Zhang J, Cheville J, Yan J, Sun Y, Huang H. (2015) Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>Mol Cell</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 59:1-13. </font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font color="#000000"><font face="Times New Roman, serif">7. Liu C, Zhou Z, Chen P, Su MY, Chang CJ, Yan J, Jiang J, </font></font><font color="#000000"><font face="Times New Roman, serif"><b>Zhang Q</b></font></font><font color="#000000"><font face="Times New Roman, serif">. (2014) Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>Cell Research</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 24,595-609.</font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font color="#000000"><font face="Times New Roman, serif">8.</font></font><font color="#000000"><font face="Times New Roman, serif"><b> Zhang Q</b></font></font><font color="#000000"><font face="Times New Roman, serif">, Shi Q, Chen Y, Yue T, Li S, Wang B, Jiang J. (2009) Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>PNAS</b></i></font></font><font color="#000000"><font face="Times New Roman, serif"> . 106(50):21191-6.</font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font face="Times New Roman, serif">9. </font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Zhang%20L%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Zhang L</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Ren%20F%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Ren F</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Zhang%20Q%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none"><b>Zhang Q</b></span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Chen%20Y%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Chen Y</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Wang%20B%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Wang B</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Jiang%20J%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Jiang J</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">. (2008) The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>Dev Cell</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 14, 377-387. </font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font face="Times New Roman, serif">10. </font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Zhang%20Q%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none"><b>Zhang Q</b></span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Zhang%20L%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Zhang L</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Wang%20B%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Wang B</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Ou%20CY%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Ou CY</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Chien%20CT%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Chien CT</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Jiang%20J%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Jiang J</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">. (2006) A Hedgehog-induced BTB protein modulates Hedgehog signaling responses by degrading Ci/Gli transcription factor. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>Dev Cell</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 10, 719-729.</font></font></p> <p style="margin-left: 0.33in; text-indent: -0.33in; margin-bottom: 0in"> <font face="Times New Roman, serif">11. </font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Jia+J%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Jia J</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Zhang+L%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Zhang L</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Zhang+Q%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none"><b>Zhang Q</b></span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Tong+C%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Tong C</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Wang+B%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Wang B</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Hou+F%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Hou F</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Amanai+K%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Amanai K</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">, </font></font><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term=%22Jiang+J%22%5BAuthor%5D"><font color="#000000"><font face="Times New Roman, serif"><span style="text-decoration: none">Jiang J</span></font></font></a><font color="#000000"><font face="Times New Roman, serif">. (2005) Phosphorylation of Cubitus interruptus by Double-time/CKIe and CKIa targets it for Slimb/b-TRCP mediated proteolytic processing. </font></font><font color="#000000"><font face="Times New Roman, serif"><i><b>Dev Cell</b></i></font></font><font color="#000000"><font face="Times New Roman, serif">. 9, 819-830.</font></font></p> <p align="LEFT" style="margin-bottom: 0in; widows: 2; orphans: 2"><br/> </p> <p align="LEFT" style="margin-bottom: 0in; widows: 2; orphans: 2"><br/> </p> <p align="LEFT" style="margin-bottom: 0in; widows: 2; orphans: 2"><br/> </p> <p align="LEFT" style="margin-bottom: 0in; widows: 2; orphans: 2"><br/> </p> <p align="LEFT" style="margin-bottom: 0in; widows: 2; orphans: 2"><br/> </p> <p align="LEFT" style="widows: 2; orphans: 2"><br/> </p> </td> </tr> <tr> <td colspan="6" width="575" height="24"> <p align="CENTER"><font face="文泉驛正黑"><span lang="zh-CN"><b>承担</b><b>科研项目</b></span></font><font face="Damascus, serif"><font size="2" style="font-size: 9pt"><b>[</b></font></font><font face="文泉驛正黑"><span lang="zh-CN"><font size="2" style="font-size: 9pt"><b>项目负责人</b></font></span></font><font face="Damascus, serif"><font size="2" style="font-size: 9pt"><b>]</b></font></font></p> </td> </tr> <tr> <td colspan="6" width="575" height="558"> <p align="LEFT" style="margin-bottom: 0in"><font face="宋体, serif">1. </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">国家自然科学基金委员会</font></span></font><font face="宋体, serif">, </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">面上项目</font></span></font><font face="宋体, serif">,Cak</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">调节</font></span></font><font face="宋体, serif">hedgehog</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">通路活性机制研究</font></span></font><font face="宋体, serif">, 2021-01-01</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">至 </font></span></font><font face="宋体, serif">2024-12-31</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">。</font></span></font></p> <p align="LEFT" style="margin-bottom: 0in"><font face="宋体, serif">2. </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">国家自然科学基金委员会，面上项目，</font></span></font><font face="宋体, serif">Cos2/PKA</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">复合体调节</font></span></font><font face="宋体, serif">Hedgehog </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">通路活性机制研究，</font></span></font><font face="宋体, serif">2018-01</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">至</font></span></font><font face="宋体, serif">2021-12</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">。</font></span></font></p> <p align="LEFT" style="margin-bottom: 0in"><font face="宋体, serif">3. </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">国家自然科学基金委员会，面上项目，</font></span></font><font face="宋体, serif">HRK</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">调节</font></span></font><font face="宋体, serif">Hedgehog</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">信号转导的分子机制研究，</font></span></font><font face="宋体, serif">2013-01</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">至</font></span></font><font face="宋体, serif">2016-12</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">。</font></span></font></p> <p align="LEFT" style="margin-bottom: 0in"><font face="宋体, serif">4. </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">国家重点基础研究发展计划，</font></span></font><font face="宋体, serif">2011CB943900</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">，发育过程中形态发生素梯度形成和信号转导的调控机制。</font></span></font><font face="宋体, serif">2011-01</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">至</font></span></font><font face="宋体, serif">2015-08</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">。</font></span></font></p> <p align="LEFT" style="margin-bottom: 0in"><font face="宋体, serif">5. </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">国家自然科学基金委员会，面上项目，</font></span></font><font face="宋体, serif">HMF</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">调节</font></span></font><font face="宋体, serif">Hedgehog</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">信号转导的分子机制研究，</font></span></font><font face="宋体, serif">2011-01</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">至</font></span></font><font face="宋体, serif">2013-12</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">。</font></span></font></p> <p align="LEFT" style="margin-bottom: 0in"><font face="宋体, serif">6. </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">国家重点基础研究发展计划，</font></span></font><font face="宋体, serif">2010CB945100</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">，卵巢早衰的分子机制及其生物标记的研究。</font></span></font><font face="宋体, serif">2010-01</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">至</font></span></font><font face="宋体, serif">2014-08</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">。</font></span></font></p> <p align="LEFT" style="margin-bottom: 0in"><font face="宋体, serif">7. </font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">国家自然科学基金委员会，面上项目，</font></span></font><font face="宋体, serif">BBK4</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">调节</font></span></font><font face="宋体, serif">Hedgehog</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">信号转导的分子机制研究，</font></span></font><font face="宋体, serif">2010-01</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">至</font></span></font><font face="宋体, serif">2012-12</font><font face="文泉驛正黑"><span lang="zh-CN"><font face="宋体">。</font></span></font></p> <p style="margin-left: 0.33in; margin-bottom: 0in"><br/> </p> <p style="margin-left: 0.33in; margin-bottom: 0in"><br/> </p> <p style="margin-left: 0.33in; margin-bottom: 0in"><br/> </p> <p style="margin-left: 0.33in"><br/> </p> </td> </tr></table><p style="margin-bottom: 0in"><br/></p></div></article>
