国家自然科学基金项目“谷氨酰转移核糖核酸（ AtGluRS ）及其相互作用蛋白质在脱落酸信号传导途径中的功能研究”（ 2007-2009 ），批准号： 30671165 ，项目经费： 30 万，项目主持人

国家自然科学基金项目“ Fibrillin 在拟南芥植物细胞内的功能以及在甘蓝型油菜中的表达研究”（ 2005-2007 ），批准号： 30470927 ，项目经费： 25 万，项目主持人

主要学术成果：

利用 ABI2 为诱饵筛选并鉴定出脱落酸（ ABA ）信号传导途径中的新信号分子 Fibrillin ，通过揭示 Fibrillin 的积累介入了 ABA 所介导的 PSII 光保护的过程，从而在脱落酸应答途径、 Fibrillin 和光胁迫之间建立了一种全新的联系，并证明 Fibrillin 基因表达和其作用可能紧密地交织在脱落酸信号传导的过程中（ Yang et al., PNAS 2006 ）。与德国 Grill 教授合作发现植物激素脱落酸细胞内受体 (Yang, Dissertation, 2003; Ma et al., Science 2009) ，该项工作被称为是 “Land Marker Paper” ，被 Science 评选为 2009 年全球十大科技进展。

解析了蛋白质激酶 CARK1 通过磷酸化 ABA 受体来调控 ABA 信号的分子机理 ( Cell Discovery , 2018; JEXBOT , 2019) 以及 E3 泛素连接酶 AtRAE1, RIFP1 通过降解 ABA 受体进而参与 ABA 信号的传递 ( Plant, Cell & Environment , 2016, 2018) ；阐明一个全新的 UDP- 糖基转移酶 UGT71C5 如何在植物体内催化脱落酸 ABA( 有活性 ) 转化为 ABA-GE( 无活性 ) ，从而达到植物体内 ABA 的内稳态平衡的分子机制 ( Plant Physiology , 2015) 。

发现一个与植物、微生物的热耐受性相关的未知基因 BnTR1 。将 BnTR1 转入在水稻、烟草、拟南芥、小麦、玉米和黑麦草中也发现能够增加植物的抗逆能力。同时， TR1 也能够提高工业微生物如产苏氨酸棒状杆菌、产赖氨酸棒状杆菌和啤酒酵母等的耐热性能。因此， BnTR1 具有重要的理论意义和巨大的实际应有价值。目前，以第一发明人身份申请了 12 项有关 TR1 的国家发明专利和 2 项国际 PCT 保护权。

代表性文章：

Hsi-Hua Wang, Yao Qiu, Qin Yu, Qian Zhang, Xiaoyi Li, Jianmei Wang, Xufeng Li, Yang Zhang and Yi Yang* . Close arrangement of CARK3 and PMEIL affects ABA-mediated pollen sterility in Arabidopsis thaliana . 2020, Plant, Cell & Environment. DOI: 10.1111/pce.13871

Ruirui Yang, Tao Wang, Wensen Shi, Siyu Li, Zhibin Liu, Jianmei Wang, Yi Yang* Arabidopsis E3 Ubiquitin Ligase ATL61 Acts as a Positive Regulator in Abscisic Acid Signaling and Drought Response. 2020, BBRC DOI:10.1016/j.bbrc.2020.05.067

Yang Fang, Chengcheng Liu, Jiangyi Lin, Xufeng Li, Kambiz N. Alavian, Yi Yang* , Yulong Niu*. PhySpeTree: an automated pipeline for reconstructing phylogenetic species trees. BMC Evolutionary Biology 2019, 19:219

Xibing Xu, Tao Wang, Yulong Niu, Ke Liang, Yi Yang* (2019). The ubiquitin-like modification by ThiS and ThiF in Escherichia coli. International Journal of Biological Macromolecules 2019, 141:351-7

Xiaoyi Li, Xiangge Kong, Qi Huang, Qian Zhang, Hu Ge, Liang Zhang, Gaoming Li, Lu Peng, Zhibin Liu, Jianmei Wang, Xufeng Li, Yi Yang * . CARK1 phosphorylates subfamily III members of ABA receptors. Journal of Experimental Botany 2019, 70(2): 517-28.

Yanlin Ma, Jing Cao, Jiahan He, Qiaoqiao Chen, Xufeng Li and Yi Yang* . Molecular Mechanism for the Regulation of ABA Homeostasis During Plant Development and Stress Responses. Int. J. Mol. Sci. 2018, 19, 3643

Xiaoyi Li, Gaoming Li, Ying Li, Xiangge Kong, Liang Zhang, Jianmei Wang, Xufeng Li and Yi Yang* . ABA receptors subfamily III enhances abscisic acid sensitivity and improves drought tolerance of Arabidopsis. Int. J. Mol. Sci. 2018, 19(7), 1938

Hu Ge, Xiaoyi Li, Shisi Chen, Mengru Zhang, Zhibin Liu, Jianmei Wang, Xufeng Li, Yi Yang* . The expression of CARK1 or RCAR11 driven by synthetic promoters increases drought tolerance in Arabidopsis thaliana. Int. J. Mol. Sci. 2018, 19(7), 1945

Liang Zhang, Xiaoyi Li, Dekuan Li, Yuna Sun, Ying Li, Qin Luo, Zhibin Liu, Jianmei Wang, Xufeng Li, Hong Zhang, Zhiyong Lou* and Yi Yang* . CARK1 mediates ABA signaling by phosphorylation of ABA receptors. Cell Discovery 2018, 4:30

Xibing Xu, Ke Liang, Yulong Niu, Yan Shen, Xuedong Wan, Haiyan Li, Yi Yang* . BAH1 an E3 Ligase from Arabidopsis thaliana Stabilizes Heat Shock Factor σ ³² of Escherichia coli by Interacting with DnaK/DnaJ Chaperone Team. Current Microbiology. 2018, 75(4)

Cun Chen, Chun-Hong Liu, Jing Cai, Wei Zhang, Wei-Liang Qi, Zheng Wang, Zhi-Bin Liu, Yi Yang* . Broad-spectrum antimicrobial activity, chemical composition and mechanism of action of garlic ( Allium sativum ) extracts. Food Control 2018, 86: 117-25.

Dekuan Li , Liang Zhang , Xiaoyi Li , Xiangge Kong, Xiaoyu Wang, Ying Li, Zhibin Liu, Jianmei Wang, Xufeng Li, Yi Yang* . AtRAE1 is involved in degradation of ABA receptor RCAR1 and negatively regulates ABA signaling in Arabidopsis. Plant, Cell & Environment . 2018, 41:231-44 .

Yulong Niu ^§ , Xibing Xu ^§ , Chengcheng Liu, Tao Wang, Ke Liang, Jianmei Wang, Zhibin Liu, Xufeng Li, Yi Yang * . A novel plant E3 ligase stabilizes Escherichia coli heat shock factor σ ³² . Scientific Reports 2017, 7(e) 4045

Xibing Xu, Yulong Niu, Ke Liang, Guomin Shen, Qing Cao, Yi Yang ∗ . Analysis of pupylation of Streptomyces hygroscopicus 5008 in vitro. BBRC , 2016. 474(1): 126-30.

Tao Wang, Xiangjun Chen, Jun Han, Sichun Ma, Jianmei Wang, Xufeng Li, Hui Zhang, Zhibin Liu ∗ , Yi Yang ∗ . Effects of the cofactor binding sites on the activities of secondary alcohol dehydrogenase (SADH). International Journal of Biological Macromolecules , 2016, 88:385–91

Ying Li, Zhibin Liu, Jianmei Wang, Xufeng Li and Yi Yang* . The Arabidopsis Kelch repeat F-box E3 ligase ARKP1 plays a positive role for the regulation of abscisic acid signaling. Plant Molecular Biology Reporter . 2016, 34(3), 582-91.

Ying Li, Liang Zhang, Dekuan Li, Zhibin Liu, Jianmei Wang, Xufeng Li and Yi Yang* . The Arabidopsis F-box E3 ligase RIFP1 plays a negative role in abscisic acid signaling by facilitating ABA receptor RCAR3 degradation. Plant, Cell & Environment . 2016, 39(3), 571-582. DOI: 10.1111/pce.12639

Liang Yang, Qiaohong Liu, Zhibin Liu, Hao Yang, Jianmei Wang, Xufeng Li and Yi Yang* . Arabidopsis C3HC4-RING finger E3 ubiquitin ligase AtAIRP4 positively regulates stress-responsive abscisic acid signaling. Journal of Integrative Plant Biology , 2016, 58(1):67-80.

Zhen Liu, Jin-Ping Yan, De-Kuan Li, Qin Luo, Qiujie Yan, Zhi-Bin Liu, Li-Ming Ye, Jian-Mei Wang, Xu-Feng Li, Yi Yang ^＊ . UGT71C5, a major glucosyltransferase mediates ABA homeostasis in Arabidopsis thaliana. Plant Physiology . 2015, 167(4): 1659-70.

Dekuan Li, Ying Li, Liang Zhang, Xiaoyu Wang, Zhe Zhao, Zhiwen Tao, Jianmei Wang, Jin Wang, Min Lin, Xufeng Li and Yi Yang ^＊ . Arabidopsis ABA Receptor RCAR1/PYL9 Interacts with an R2R3-Type MYB Transcription Factor, AtMYB44. Int. J. Mol. Sci. 2014, 15, 8473-90.

Fengxi Yang, Zhibin Liu, Jianmei Wang, Xufeng Li, Yi Yang ^＊ . An auxin-responsive endogenous peptide regulates root development in Arabidopsis. Journal of Integrative Plant Biology , 2014, 56:635-47.